SYNTHESIS OF RHODODENDRIN AND EPI-RHODODENDRIN, [(R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL AND (S)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL BETA-D-GLUCOPYRANOSIDE]
K. Mori et Zh. Qian, SYNTHESIS OF RHODODENDRIN AND EPI-RHODODENDRIN, [(R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL AND (S)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL BETA-D-GLUCOPYRANOSIDE], Bulletin de la Societe chimique de France, 130(3), 1993, pp. 382-387
The first synthesis of rhododendrin 1 and epi-rhododendrin 2 [(R)- and
(S)-3-(4-hydroxyphenyl)-1-methylpropyl beta-D-glucopyranoside] was ac
hieved by starting from ethyl (S)-3-hydroxybutanoate 4, p-bromoanisole
and D-glucose. Rhododendrin 1 is known as the hepatoprotective consti
tuent of Taxus baccata L.