AN EXPEDITIOUS ASYMMETRIC-SYNTHESIS OF (-)-(1R,2S)-CISPENTACIN

Authors
DAVIES SG ICHIHARA O WALTERS IAS
Citation
Sg. Davies et al., AN EXPEDITIOUS ASYMMETRIC-SYNTHESIS OF (-)-(1R,2S)-CISPENTACIN, Synlett, (7), 1993, pp. 461-462
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
7
Year of publication
1993
Pages
461 - 462
Database
ISI
SICI code
0936-5214(1993):7<461:AEAO(>2.0.ZU;2-J
Abstract
The antifungal antibiotic (-)-(1R,2S)-2-aminocyclopentane-1-carboxylic acid (cispentacin) 4 has been prepared via the highly stereoselective conjugate addition reaction of lithium (S)-(alpha-methylbenzyl)benzyl amide (S)-2 to tert-butyl 1-cyclopentene-1-carboxylate 1.