IMPROVED HORNER-WADSWORTH-EMMONS OLEFINATION OF BASE SENSITIVE GAMMA-CHIRAL BETA-KETOPHOSPHONATES

Authors
KOSKINEN AMP KOSKINEN PM
Citation
Amp. Koskinen et Pm. Koskinen, IMPROVED HORNER-WADSWORTH-EMMONS OLEFINATION OF BASE SENSITIVE GAMMA-CHIRAL BETA-KETOPHOSPHONATES, Synlett, (7), 1993, pp. 501-502
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
7
Year of publication
1993
Pages
501 - 502
Database
ISI
SICI code
0936-5214(1993):7<501:IHOOBS>2.0.ZU;2-7
Abstract
A new modification for the Homer-Wadsworth-Emmons reaction, utilizing K2CO3/MeCN as the base/solvent system, has been developed. The modific ation is particularly advantageous with base labile chiral phosphonate s, exemplified by 1 derived from L-serine.