Virtually all segments of the gastrointestinal tract have been used su
ccessfully in augmentation cystoplasty. The complications inherent in
enterocystoplasty are well described. Megaureters subtending effete ki
dneys (poorly or nonfunctioning) provide a novel and excellent source
of augmentation material with urothelium and muscular backing, free of
the electrolyte and acid base disturbances, and mucus production that
plague enterocystoplasty. Augmentation cystoplasty using detubularize
d, reconfigured, otherwise disposable megaureter, with or without ipsi
lateral total or partial nephrectomy, was performed in 16 patients (me
an age 8.8 years, range 1 to 25) with inadequate and dysfunctional bla
dders. Postoperative followup varied between 8 and 38 months (mean 22)
. The overall renal function and radiographic appearance of the remain
ing upper tracts have remained stable or improved in all patients. Of
the 16 patients 15 require intermittent catheterization and 1 voids sp
ontaneously. Ten patients are continent day and night, 5 have improved
continence (4 damp at night and 1 stress incontinence) and 1 has fail
ed to gain continence despite good capacity and compliance. Complete p
ostoperative urodynamic evaluations in 12 of 13 patients show good cap
acity, low pressure bladders with no instability. Complications occurr
ed in 5 patients, including transient urine extravasation in 2, contra
lateral ureterovesical obstruction in 2 and Mitrofanoff stomal stenosi
s in 1. Augmentation ureterocystoplasty combines the benefits common t
o all enterocystoplasties without adding any of the untoward complicat
ions or risks associated with nonurothelial augmentations.