Pure squamous carcinoma is a rare pancreas cancer histological variety
. Moreover the association of malign humoral hypercalcemia and neoplas
ia of the pancreas exocrine portion is extremely rare. The case of a p
atient with pure squamous pancreas carcinoma and hypercalcemia is disc
ussed. The absence of bone metastasis allowed to classify it within th
e malign humoral hypercalcemia syndrome. It is the first case describe
d in the spanish scientific literature and the third in the internatio
nal literature of an epidermoid pancreas carcinoma associated to malig
n humoral hypercalcemia.