DIVERGENT DIFFERENTIATION IN SMALL ROUND-CELL TUMORS OF THE SOFT-TISSUES WITH NEURAL FEATURES - AN ANALYSIS OF 10 CASES

Authors
PEARSON JM HARRIS M EYDEN BP BANERJEE SS
Citation
Jm. Pearson et al., DIVERGENT DIFFERENTIATION IN SMALL ROUND-CELL TUMORS OF THE SOFT-TISSUES WITH NEURAL FEATURES - AN ANALYSIS OF 10 CASES, Histopathology, 23(1), 1993, pp. 1-9
Citations number
30
Categorie Soggetti
Cytology & Histology",Pathology
Journal title
Histopathology → ACNP
ISSN journal
03090167
Volume
23
Issue
1
Year of publication
1993
Pages
1 - 9
Database
ISI
SICI code
0309-0167(1993)23:1<1:DDISRT>2.0.ZU;2-B
Abstract
A series of 10 small round-cell tumours, having in common evidence of neural differentiation, were investigated by immunohistochemistry and electronmicroscopy. In seven, evidence of divergent muscle and/or epit helial differentiation was found. This phenomenon thus appears more co mmon than previously appreciated and suggests that there may be a cont inuous and overlapping phenotypic spectrum from Ewing's tumour of soft tissue to intra-abdominal desmoplastic small cell tumour.