NO LOSS IN TOTAL NEURON NUMBER IN THE THALAMIC RETICULAR NUCLEUS AND NEOCORTEX IN THE GENETIC ABSENCE EPILEPSY RATS FROM STRASBOURG

Authors
SABERS A MOLLER A SCHEELKRUGER J DAM AM
Citation
A. Sabers et al., NO LOSS IN TOTAL NEURON NUMBER IN THE THALAMIC RETICULAR NUCLEUS AND NEOCORTEX IN THE GENETIC ABSENCE EPILEPSY RATS FROM STRASBOURG, Epilepsy research, 26(1), 1996, pp. 45-48
Citations number
27
Categorie Soggetti
Clinical Neurology
Journal title
Epilepsy research → ACNP
ISSN journal
09201211
Volume
26
Issue
1
Year of publication
1996
Pages
45 - 48
Database
ISI
SICI code
0920-1211(1996)26:1<45:NLITNN>2.0.ZU;2-2
Abstract
The thalamic reticular nucleus (nRt) as well as the neocortex are invo lved in the bilateral spike- and wave-discharge loop in genetic absenc e epilepsy rats from Strasboug (GAERS). Neuron loss in different brain areas has been described in relation to epilepsy with convulsive seiz ures. We have previously investigated the ventrolateral/posterior nucl eus of thalamus in GAERS and found no neuron loss. We applied the same efficient and unbiased stereological methods to nRt and to neocortex and again found no loss of neurons. The oscillatory properties of nRt are not related to neuron loss.