A CONVENIENT SYNTHESIS OF ALKYNYLPYRAZOLES

Authors
YOSHIMATSU M KAWAHIGASHI M HONDA E KATAOKA T
Citation
M. Yoshimatsu et al., A CONVENIENT SYNTHESIS OF ALKYNYLPYRAZOLES, Journal of the Chemical Society. Perkin transactions. I, (5), 1997, pp. 695-700
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
5
Year of publication
1997
Pages
695 - 700
Database
ISI
SICI code
0300-922X(1997):5<695:ACSOA>2.0.ZU;2-T
Abstract
Diazomethane add to the enyne sulfones 1, 3, 4, 6-11 regio- and stereo -selectively to give the -alkynyl-5-phenylsulfonyl-4,5-dihydro-3H-pyra zoles 12-15 and 17-19, which are converted by MeLi into the 4-alkynyl- 1N-pyrazoles 24, 25, 16, 26, 28, 30 in good yields, 4,5-Bis(alkynyl)-1 H-pyrazoles 34, 37 are also obtained by the same procedure.