APPLICATION OF FLOW-CYTOMETRY TO THE STUDY OF ANTIPHAGOCYTIC PROPERTIES OF KLEBSIELLA-PNEUMONIAE CAPSULAR POLYSACCHARIDE

Authors
RUIZ C SABIO JM SANTOS JL MONTES MJ OLIVARES EG
Citation
C. Ruiz et al., APPLICATION OF FLOW-CYTOMETRY TO THE STUDY OF ANTIPHAGOCYTIC PROPERTIES OF KLEBSIELLA-PNEUMONIAE CAPSULAR POLYSACCHARIDE, FEMS immunology and medical microbiology, 7(1), 1993, pp. 63-66
Citations number
16
Categorie Soggetti
Immunology,Microbiology
Journal title
FEMS immunology and medical microbiology → ACNP
ISSN journal
09288244
Volume
7
Issue
1
Year of publication
1993
Pages
63 - 66
Database
ISI
SICI code
0928-8244(1993)7:1<63:AOFTTS>2.0.ZU;2-M
Abstract
We used flow cytometry to compare the effects of whole cells and capsu lar polysaccharides of Klebsiella pneumoniae on the phagocytic ability ot polymorphonuclear leukocytes. Our results showed a light descrease in phagocytic activity in the presence of capsular polysaccharides, b ut a marked decrease with whole cells. Our findings suggest that the r esistance to phagocytosis in these microorganisms is not due exclusive ly to their capsule, as claimed by other authors.