The main habitat of Eubacterium suis (E. suis) is the preputial divert
iculum of male pigs. E. suis can be transmitted from boars to sows at
the time of mating, and ascending urinary tract infections (cystitis a
nd pyelonephritis) in sows may develop. In this paper different method
s of treatment were investigated to eliminate E. suis from the diverti
culum of carrier boars (n = 33). Local therapy and feed medication wer
e administered separately or in combination. For local instillation in
to the preputial sac penicillin, penicillin/streptomycin or enrofloxac
in were used, while medicated feed contained enrofloxacin. None of the
treatments resulted in boars, which were persistently free from E. su
is. Also additional hygiene measures as washing of boars and desinfect
ion of pens could not improve the results. At the latest 18 days after
treatment E. suis could be detected again in the preputial diverticul
um of all boars. Short duration of action of antibiotics in the preput
ial sac as well as re-colonisation of the diverticulum by contaminated
pens are discussed. In herds in which urinary tract infections are tr
oublesome it is worthwhile using artificial insemination to prevent tr
ansmission of E. suis to the sow. Treatment of unspecific urinary trac
t infections in sows may be also important, because alterations of bla
dder mucosa due to other bacteria may support the colonisation of E. s
uis.