TRANSMISSIBILITY OF THE D-VARIANT OF ENCEPHALOMYOCARDITIS VIRUS (EMC-D) IN MICE

Authors
DOI C TAKEDA M HIRASAWA K DOI K
Citation
C. Doi et al., TRANSMISSIBILITY OF THE D-VARIANT OF ENCEPHALOMYOCARDITIS VIRUS (EMC-D) IN MICE, Laboratory animals, 27(3), 1993, pp. 222-225
Citations number
4
Categorie Soggetti
Veterinary Sciences
Journal title
Laboratory animals → ACNP
ISSN journal
00236772
Volume
27
Issue
3
Year of publication
1993
Pages
222 - 225
Database
ISI
SICI code
0023-6772(1993)27:3<222:TOTDOE>2.0.ZU;2-W
Abstract
Transmissibility of the D variant of encephalomyocarditis virus (EMC-D ) was examined. Eight-week-old ICR:CD-1 male mice inoculated with 10(5 ) plaque forming units (PFU)/animal of EMC-1) intranasally, orally or intraperitoneally showed marked viraemia and prominent pancreatic lesi ons at 2 days after inoculation (2 DAI), and excreted virus in faeces from 2 to 8 DAI (virus titre:10(3)-10(5) PFU/g). Only a small proporti on of control mice housed with EMC-D-inoculated mice for 10 days devel oped viraemia and pancreatic lesions.