An overview is presented of immortals, institutions, and discoveries o
f past ages which have contributed to the furtherance of clinical scie
nce. The presentation is divided into two parts: I. Noteworthy contrib
utions to the development of clinical science-1500 to 1700 A.D. II. No
teworthy contributions to the development of clinical science-1700 to
1949 A.D. The time has come for a transformation and rejuvenation of c
linical laboratories in hospitals and medical institutions in our coun
try. In recent years, the clinical investigative mission of hospital l
aboratories has been grossly neglected owing, in large measure, to the
increased work loads for analytical service that are required for pat
ient care. However, commercial corporations have now gradually invaded
the field of clinical laboratory services, so that in the foreseeable
future clinical laboratories will be afforded more time and opportuni
ties for fulfillment of the investigative mission. The objectives of c
linical science are to conserve health and to cure disease. By promoti
ng the investigative point of view, clinical science will be destined
to contribute to the furtherance of its objectives.