BIOSYNTHESIS IN-VITRO OF 2-(3-AMINO-3-CARBOXYPROPYL)-ISOXAZOLIN-5-ONE, THE NEUROTOXIC AMINO-ACID IN LATHYRUS-ODORATUS

Authors
IKEGAMI F SAKAI R ISHIKAWA T KUO YH LAMBEIN F MURAKOSHI I
Citation
F. Ikegami et al., BIOSYNTHESIS IN-VITRO OF 2-(3-AMINO-3-CARBOXYPROPYL)-ISOXAZOLIN-5-ONE, THE NEUROTOXIC AMINO-ACID IN LATHYRUS-ODORATUS, Biological & pharmaceutical bulletin, 16(7), 1993, pp. 732-734
Citations number
17
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Biological & pharmaceutical bulletin → ACNP
ISSN journal
09186158
Volume
16
Issue
7
Year of publication
1993
Pages
732 - 734
Database
ISI
SICI code
0918-6158(1993)16:7<732:BIO2>2.0.ZU;2-I
Abstract
2-(3-Amino-3-carboxypropyl)-isoxazolin-5-one (ACI), a neurotoxic amino acid from Lathyrus odoratus, was confirmed to be derived enzymaticall y from S-adenosyl-L-methionine (SAM) and isoxazolin-5-one. Some proper ties of an enzyme in the biosynthesis of ACI are described.