INTRANASAL CAFFEINE AND AMPHETAMINE CAUSING STROKE

A 37 year-old man with an ischaemic stroke after the nasal use of amph etamine and caffeine is reported. Transient arterial hypertension due to these agents may have been the mediator of the stroke. Mitral annul ar calcification was the only other abnormality found, and was thought not to play an important role in this patient. There was no evidence of a primary or secondary hypercoagulable state. Stroke due to nasal u se of these agents appears not to have been previously reported (Medli ne(R) literature search 1983-1993).