COMPRESSION STRENGTH OF DONOR BONE FOR POSTERIOR LUMBAR INTERBODY FUSION

Forty-three blocks of allograft bone used clinically for Posterior lum bar interbody fusion and twenty-three blocks of xenograft bone from go ats and cows were tested in compression and compared with the clinical mechanical requirements of posterior lumbar interbody fusion. Variati ons in processing methods allowed evaluation of the effects of process ing on mechanical strength. Fresh-frozen cancellous bone from Os Bone (Cleveland, OH) failed at an average load of 863 +/- 615 N. Fresh-froz en cancellous bone from the Mid American Tissue Center (Massilon, OH)f ailed at an average load of 3492 +/- 1720 N. Freeze-dried cancellous b one obtained from the American Red Cross failed at an average load of 1595 +/- 1031 N. Air-dried ethylene oxide sterilized cancellous bone f rom Os Bone failed at an average load of 1338 +/- 691 N. Air-dried eth ylene oxide sterilized cancellous bone from Mid America failed at an a verage load of 1616 +/- 1157 N. Fresh-frozen tricortical bone from Mid America failed at an average load of 2257 +/- 1081 N. Air-dried ethyl ene oxide sterilized tricortical bone from Os Bone failed at an averag e load of 2474 +/- 1928 N. Air-dried ethylene oxide sterilized tricort ical bone from Mid America failed at an average load of 2308 +/- 422 N . Bovine Surgibone from Unilab (Hillside, NJ) failed at an average loa d of 2967 +/- 399 N. Strength of bone in compression was not weakened by freeze drying, air drying, ethylene oxide sterilization, or by incu bation at 37-degrees-C for 1 week before testing. Four of nine blocks of fresh-frozen cancellous bone, seven of nineteen blocks of ethylene oxide sterilized cancellous bone and three of eighteen blocks of trico rtical bone were of insufficient strength for unsupported use in inter body fusion. Radiographic density of the bone correlated with strength of bone in compression testing but did not provide a useful index of bone strength.