SYNTHESIS OF NATURALLY-OCCURRING 4-ALKYLIDENEGLUTAMIC ACIDS

Authors
MOODY CM YOUNG DW
Citation
Cm. Moody et Dw. Young, SYNTHESIS OF NATURALLY-OCCURRING 4-ALKYLIDENEGLUTAMIC ACIDS, Tetrahedron letters, 34(29), 1993, pp. 4667-4670
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
29
Year of publication
1993
Pages
4667 - 4670
Database
ISI
SICI code
0040-4039(1993)34:29<4667:SON4A>2.0.ZU;2-I
Abstract
The enaminone (4), prepared from (2S)-pyroglutamic acid, has been reac ted with Grignard reagents to afford a variety of (E)-alkylidene deriv atives (8). Three of these have been converted to the 4-alkylideneglut amic acids, (1), (2) and (3), which are identical to known natural pro ducts, (2) and (3) being the E-isomers.