SPINAL EVOKED-POTENTIAL IN PATIENTS UNDERGOING THORACOABDOMINAL AORTIC RECONSTRUCTION - A PROGNOSTIC INDICATOR OF POSTOPERATIVE MOTOR DEFICIT

Citation
K. Grabitz et al., SPINAL EVOKED-POTENTIAL IN PATIENTS UNDERGOING THORACOABDOMINAL AORTIC RECONSTRUCTION - A PROGNOSTIC INDICATOR OF POSTOPERATIVE MOTOR DEFICIT, Journal of clinical monitoring, 9(3), 1993, pp. 186-190
Citations number
16
Categorie Soggetti
Medical Laboratory Technology
ISSN journal
07481977
Volume
9
Issue
3
Year of publication
1993
Pages
186 - 190
Database
ISI
SICI code
0748-1977(1993)9:3<186:SEIPUT>2.0.ZU;2-Q
Abstract
We studied 76 patients who had thoracoabdominal aortic reconstruction between january 1981 and March 1991. Evoked potential monitoring of th e spinal cord (peridural bipolar catheter stimulation at level L4-L5, recording via a second bipolar catheter at level Th4) was used to pred ict intraoperatively a possible motor deficit. There was a close linea r correlation of r = 0.892 between postoperative motor deficit (normal , paraparesis, paraplegia) and the time from declamping to reappearanc e of the potential. Forty-three of 76 patients received prostaglandin E1 (5 ng/kg/min) for pharmacologic protection of the spinal cord 15 mi nutes before onset of clamping and through the entire clamping period. Patients with protection had a loss of their potential significantly later (20.2 min; p < 0.05) than those patients who had not received an y pharmacologic treatment (15.2 min). Pharmacologic protection also re sulted in a reduced incidence of postoperative neurologic deficit and paraplegia when compared with patients receiving no treatment (25% vs 5%). These data suggest that spinal evoked potentials may be very usef ul for monitoring during these hazardous cases. They also suggest that pharmacologic protection before clamping may help preserve the functi on of the spinal cord during aortic clamping.