THE THEORETICAL-ANALYSIS OF THE PROCESS OF RNA MOLECULE SELF-ASSEMBLY

Citation
A. Kister et al., THE THEORETICAL-ANALYSIS OF THE PROCESS OF RNA MOLECULE SELF-ASSEMBLY, Biosystems, 30(1-3), 1993, pp. 31-48
Citations number
33
Categorie Soggetti
Biology
Journal title
ISSN journal
03032647
Volume
30
Issue
1-3
Year of publication
1993
Pages
31 - 48
Database
ISI
SICI code
0303-2647(1993)30:1-3<31:TTOTPO>2.0.ZU;2-T
Abstract
The Kinetic approach to the problem of the RNA structure prediction ba sed on the analysis of the molecule self-formation is proposed. Re-str ucturization that occurs during processing is described in terms of Ma rkov processes. A new formalism designating nucleotides by complex num bers is proposed, leading to the complex unitary space of nucleic vect ors. Properties of structure and transition matrices are discussed in relation to the analysis of RNA structural formation processes. The no n-linear dynamic behavior of secondary structure transitions is analyz ed. Soliton-like oscillations of RNA and DNA tertiary structures are p redicted. The Monte-Carlo simulation of the RNA structure self-formati on is used to calculate the ensemble of the secondary structures of th e tRNA(Ala) precursor from Bombix mori formed during processing.