DOPAMINE-D2 RECEPTOR ALTERATION IN PATIENTS WITH PERIODIC MOVEMENTS IN SLEEP (NOCTURNAL MYOCLONUS)

Authors
STAEDT J STOPPE G KOGLER A MUNZ D RIEMANN H EMRICH D RUTHER E
Citation
J. Staedt et al., DOPAMINE-D2 RECEPTOR ALTERATION IN PATIENTS WITH PERIODIC MOVEMENTS IN SLEEP (NOCTURNAL MYOCLONUS), Journal of neural transmission, 93(1), 1993, pp. 71-74
Citations number
15
Categorie Soggetti
Neurosciences
Journal title
Journal of neural transmission → ACNP
ISSN journal
03009564
Volume
93
Issue
1
Year of publication
1993
Pages
71 - 74
Database
ISI
SICI code
0300-9564(1993)93:1<71:DRAIPW>2.0.ZU;2-O
Abstract
Periodic movements in sleep (PMS) can cause severe sleep disturbances. We investigated the central dopamine D2 receptor density in patients with PMS with I-123-IBZM and single photon emission tomography (SPET). In PMS there was a lower I-123-I-IBZM binding in the basal ganglia co mpared to the control group. The results indicate a loss of central D2 receptors in PMS.