MULTIFOCAL GIANT-CELL GLIOBLASTOMA - CASE-REPORT

Glioblastoma multiforme (GM) of the cerebellum is a rare tumour. A var iant of GM, a multifocal giant cell glioblastoma, initially presenting in the cerebellum, has not previously been reported. A giant cell gli oblastoma occurring in a 46-year-old man who presented initially with a cerebellar tumour is described. One month after excision of the tumo ur, the patient had a grand mal seizure. Computed tomography (CT) show ed a low-density lesion in the left temporal lobe. Four months later h e developed dysphasia and right-sided hemiparesis. Repeat CT scan reve aled a large temporal lobe tumour which was excised, and histologicall y found to be a giant-cell glioblastoma with histopathological similar ities to the original cerebellar tumour. The clinical course, computed tomographic and pathological features of this tumour are described an d discussed.