The treatment of erectile failure has developed rapidly over the last
decade with the introduction of intracavernosal self injection therapy
, first with phenoxybenzamine, then with papaverine and paraverine-phe
ntolamine. These drugs are now progressively replaced by prostaglandin
E1 mainly because of its efficacy and fewer side effects. Protaglandi
n E1 can induce a rigid erection even in case of severe arteriopathy a
nd offers an excellent alternative to a prosthetic implant.