M. Bohm et al., RECURRENT PAROXYSMAL NECK SWELLINGS AS PR IMARY MANIFESTATION OF A PHEOCHROMOCYTOMA, Deutsche Medizinische Wochenschrift, 118(27-28), 1993, pp. 1011-1014
A 45-year-old female had been suffering for about 6 months almost dail
y from paroxysmal neck swellings with occasional difficulties in swall
owing and from non-specific abdominal complaints. Hormone analyses, pe
rformed because of the marked blood pressure increase up to 210/120 mm
Hg during such an attack, revealed an increase in vanillyl mandelic a
cid and epinephrine concentrations in the 24-hour urine. CT demonstrat
ed a tumour of 4 x 5 x 5 cm size in the region of the right adrenal. T
he paroxysmal neck swellings and blood pressure increase could be repr
oduced by means of pressure applied over the tumour range with the ult
rasound transducer. The tumour was extirpated and histology revealed a
phaeochromocytoma. For more than one year now the patient has been fr
ee from complaints. - To date, recurrent neck swellings have not been
reported in association with a phaeochromocytoma. Possible causes may
be an enhanced congestion of the deep neck vessels during paroxysmal b
lood pressure increase or an enhanced response by the adrenoreceptors
of these vessels to the released catecholamines.