SQUAMOID ECCRINE DUCTAL CARCINOMA

We describe three cases of a distinctive cutaneous adnexal neoplasm sh owing features of eccrine ductal differentiation that were characteriz ed by a prominent squamoid component. The tumours presented as solitar y dermal nodules on the head and neck areas and the extremities in eld erly patients. Histologically, they were characterized by a prominent squamous proliferation with atypia, keratinous cyst formation and squa mous eddies which seemed to merge with areas showing eccrine ductal di fferentiation, including ductular formations in continuity with eccrin e ductal epithelium, Clinical follow-up in one case showed multiple lo cal recurrences over a period of 3 years despite complete surgical exc ision, Squamoid eccrine ductal carcinoma should be considered in the d ifferential diagnosis of cutaneous adnexal neoplasms showing squamoid and ductal features of differentiation.