IMMUNOHISTOPATHOLOGICAL SPECTRUM IN CUTANEOUS TUBERCULOSIS

Authors
SEHGAL VN GUPTA R BOSE M SAHA K
Citation
Vn. Sehgal et al., IMMUNOHISTOPATHOLOGICAL SPECTRUM IN CUTANEOUS TUBERCULOSIS, Clinical and experimental dermatology, 18(4), 1993, pp. 309-313
Citations number
31
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
Clinical and experimental dermatology → ACNP
ISSN journal
03076938
Volume
18
Issue
4
Year of publication
1993
Pages
309 - 313
Database
ISI
SICI code
0307-6938(1993)18:4<309:ISICT>2.0.ZU;2-B
Abstract
Granulomas of lupus vulgaris were characterized by a raised CD4+/CD8ratio, while in scrofuloderma this was significantly decreased. Tuberc ulosis verrucosa cutis showed intermediate changes. These immunologica l variations suggest that cutaneous tuberculosis forms a spectrum with strong cell-mediated immunity seen in lupus vulgaris, and weaker cell -mediated responses in scrofuloderma; tuberculosis verrucosa cutis is intermediate between the two.