A patient with dermatitis herpetiformis (DH) developed abnormal liver
function tests and was found to have histological features of primary
sclerosing cholangitis (PSC) on liver biopsy. The association of DH an
d PSC has not been previously reported and the high incidence of pheno
type HLA B8 and DR3 in these disorders suggests a common genetic predi
sposition may exist for both diseases.