Cg. Wang et al., SYNTHESIS OF (3'-5'),(2'-5')-LINKED DI-ADENYLYL AND TRI-ADENYLYL METHYLPHOSPHONATE ANALOGS, Nucleic acids research, 21(14), 1993, pp. 3245-3248
Stereoselectivity was found during the coupling reaction, to form 2',5
'- and 3',5'-linked di- and triadenylyl methylphosphonate. The configu
ration of phosphorus was determined by (HNMR)-H-1 NOE.