ISOPALINURIN - A MILD PROTEIN PHOSPHATASE INHIBITOR FROM A SOUTHERN AUSTRALIAN MARINE SPONGE, DYSIDEA SP

Authors
MURRAY L SIM ATR ROSTAS JAP CAPON RJ
Citation
L. Murray et al., ISOPALINURIN - A MILD PROTEIN PHOSPHATASE INHIBITOR FROM A SOUTHERN AUSTRALIAN MARINE SPONGE, DYSIDEA SP, Australian Journal of Chemistry, 46(8), 1993, pp. 1291-1294
Citations number
20
Categorie Soggetti
Chemistry
Journal title
Australian Journal of Chemistry → ACNP
ISSN journal
00049425
Volume
46
Issue
8
Year of publication
1993
Pages
1291 - 1294
Database
ISI
SICI code
0004-9425(1993)46:8<1291:I-AMPP>2.0.ZU;2-5
Abstract
A new sesterterpene tetronic acid, isopalinurin (1), has been isolated from an Australian marine sponge, Dysidea sp., collected in Bass Stra it. Isopalinurin (1) was identified as the agent responsible for the a ntibiotic activity and protein phosphatase inhibitory properties exhib ited by the crude ethanol extract, and its structure was secured by de tailed spectroscopic analysis.