Lo. Zamir et al., EVIDENCE FOR ENZYMATIC FORMATION OF ISOPREPHENATE FROM ISOCHORISMATE, Bioorganic & medicinal chemistry letters, 3(7), 1993, pp. 1441-1446
Isoprephenate, a hypothetical intermediate in the biosynthesis of m-ca
rboxy aromatic amino acids, has not been demonstrated in vitro or in v
ivo. Evidence for The enzymatic conversion of isochorismate to isoprep
henate was obtained in crude extracts derived from Nicotiana silvestri
s.