The antimicrobial activity of the 10 most abundant flavor compounds of
the cashew Anacardium occidentale (Anacardiaceae) apple has been test
ed. Most of them exhibited some activity against one or more of 14 mic
roorganisms. Noticeably, (E)-2-hexenal showed activity against all of
the microorganisms tested, including Gram-negative bacteria. In additi
on, the antibacterial activity of indole against Escherichia coli was
enhanced 4-fold by combining it with a sublethal amount of (E)-2-hexen
al. Furthermore, the minimum inhibitory concentration of this combinat
ion was found to be bactericidal by the time-kill curve method.