Rjs. Briggs et al., LARYNGEAL IMAGING BY COMPUTERIZED-TOMOGRAPHY AND MAGNETIC-RESONANCE FOLLOWING RADIATION-THERAPY - A NEED FOR CAUTION, Journal of Laryngology and Otology, 107(6), 1993, pp. 565-568
For patients with laryngeal tumours, the use of computerized tomograph
y (CT) or magnetic resonance imaging (MR) may facilitate accurate stag
ing by the demonstration of cartilage invasion or tumour extension to
areas such as the pre-epiglottic space. The role of imaging in the fol
low-up of patients after radiotherapy, however, has not been examined.
A prospective study of 18 patients undergoing laryngectomy was perfor
med. The results of pre-operative CT and MR imaging were correlated wi
th the pathological findings from whole organ axial sections of the la
ryngeal specimens. In five patients (28 per cent) both CT and MR image
s were significantly impaired by movement artefact. In the eight patie
nts without previous radiotherapy, seven had adequate quality imaging
and both CT and MR accurately demonstrated the site, size and extent o
f laryngeal tumour. In eight of die ten patients following radiation t
herapy die presence of tumour was correctly identified, however there
was a poor correlation between the imaging and pathological findings.
Two patients had radionecrosis alone. Neither CT nor MR imaging could
differentiate between radionecrosis and recurrent tumour.