FRUSEMIDE-INDUCED BULLOUS PEMPHIGOID

Bullous pemphigoid is a rare complication of frusemide therapy. We pre sent two patients in whom the link between frusemide and this conditio n was not recognised early, and continued frusemide therapy resulted i n prolonged leg blistering and ulceration. On withdrawing the drug, al l lesions in both patients resolved completely. Although uncommon, thi s frusemide reaction needs to be borne in mind as it can add to the mo rbidity of elderly patients with heart failure.