It is always important to treat conditions which may be cancerous with
respect and, where there is suspicion, to take biopsies for histologi
cal examination. A hoarse voice may, in addition,be a sign of tubercul
osis of the larynx, and the clinical appearance can be similar to a ca
rcinoma. Preoperative chest X-ray (not always performed) and an awaren
ess by the histologist of such a possibility are important now that th
is condition is increasing in frequency in parallel with conditions wh
ere immunological status is compromised.