Jn. Volff et al., NUCLEOTIDE-SEQUENCE ANALYSIS OF THE JUNCTIONS OF THE TERMINAL INVERTED REPEATS OF THE STREPTOMYCES-LIVIDANS LINEAR CHROMOSOME, MGG. Molecular & general genetics, 253(6), 1997, pp. 761-765
The junctions of the Streptomyces lividans chromosomal terminal invert
ed repeats (TIRs) were isolated from cosmid clones as 6.2 kb PstI and
2.9 kb BamHI fragments, respectively. The fragments were completely se
quenced. In each of the fragments just one open reading frame could be
identified. One putative gene product showed significant similarities
to a sensor and the other to a transcriptional regulator protein of p
rokaryotic two-component signalling systems. Next to one TIR numerous
long direct repeats were found within a region of about 400 bp.