COMPARISON OF URODYNAMIC FINDINGS AND RESPONSE TO OXYBUTYNIN IN NOCTURNAL ENURESIS

Sixty-three children with persistent nocturnal enuresis were urodynami cally assessed and subsequently treated with oxybutynin chloride. Urod ynamic evaluation, including graduation of detrusor instability and co mparison of maximum bladder capacity with the age-predicted norm, conf irmed an inadequate storage function in 84% of the children. Treatment benefit totaling 70% was dependent upon urodynamic findings, with bes t relation to the determined bladder capacity. The value attributed to graduation of uninhibited contractions was prognostic in accordance w ith further subdivision of the maximum bladder capacity. Treatment ben efit was limited in children with normal urodynamic findings.