PHARMACOLOGICAL EVALUATION OF THE ALPHA-ADRENOCEPTORS OF THE RABBIT URETHRA

Authors
CHEN HI HU P FAN PL BRADING AF
Citation
Hi. Chen et al., PHARMACOLOGICAL EVALUATION OF THE ALPHA-ADRENOCEPTORS OF THE RABBIT URETHRA, European urology, 24(1), 1993, pp. 144-147
Citations number
5
Categorie Soggetti
Urology & Nephrology
Journal title
European urology → ACNP
ISSN journal
03022838
Volume
24
Issue
1
Year of publication
1993
Pages
144 - 147
Database
ISI
SICI code
0302-2838(1993)24:1<144:PEOTAO>2.0.ZU;2-I
Abstract
Nerve-mediated responses of the rabbit urethral smooth muscles were st udied using electrical stimuli of short duration to selectively stimul ate the intramural nerves. The nature of the responses to exogenously applied adrenergic agonists and its antagonists were also examined. Th e results confirmed that the rabbit urethral smooth muscle contains bo th subtypes of alpha-adrenoceptors and the nerve-mediated contraction of the rabbit urethra is of adrenergic nature and mediated mainly via al-adrenoceptors [1].