EARLY DIAGNOSIS OF PROSTATIC-CARCINOMA MAY BE ACHIEVED THROUGH IN-VITRO CULTURE OF TUMOR-CELLS HARVESTED BY PROSTATIC MASSAGE

Authors
BOLOGNA M VICENTINI C CORRAO G FESTUCCIA C MUZI P TUBARO A BIORDI L MIANO L
Citation
M. Bologna et al., EARLY DIAGNOSIS OF PROSTATIC-CARCINOMA MAY BE ACHIEVED THROUGH IN-VITRO CULTURE OF TUMOR-CELLS HARVESTED BY PROSTATIC MASSAGE, European urology, 24(1), 1993, pp. 148-155
Citations number
20
Categorie Soggetti
Urology & Nephrology
Journal title
European urology → ACNP
ISSN journal
03022838
Volume
24
Issue
1
Year of publication
1993
Pages
148 - 155
Database
ISI
SICI code
0302-2838(1993)24:1<148:EDOPMB>2.0.ZU;2-U
Abstract
As a new method for early diagnosis of prostatic carcinoma we succeede d in growing in vitro the epithelial cells which can be collected from prostatic fluid after rectal prostatic massage. We report here the up dated and statistically analyzed series of data (174 patients) on this new approach, which allows all the harvested cells to express their b iological features. The method reaches a sensitivity of 72-86% and a s pecificity of 88-100%. This noninvasive test, which is also suitable f or mass screening, may be very useful for an early diagnosis of the ne oplasm.