M. Gonella et al., SMALL-SOLUTE CLEARANCES IN PATIENTS UNDERGOING HEMODIAFILTRATION AND HEMODIALYSIS WITH HIGHLY PERMEABLE MEMBRANES, Blood purification, 10(5-6), 1992, pp. 333-336
High-permeability artificial membranes were used in hemodialysis, in s
oft hemodiafiltration (HDF; ultrafiltration rate 68 +/- 6 ml/min), and
high-ultrafiltration HDF (ultrafiltration rate 117 +/- 7 ml/min), in
order to compare the effect of the three techniques on small-solute re
moval. Urea and creatinine clearances were significantly (p < 0.001) l
ower on hemodialysis (195 +/- 18 and 143 +/- 8 ml/min) than on soft HD
F (247 +/- 11 and 179 +/- 12 ml/min) and high-ultrafiltration HDF (236
+/- 18 and 172 +/- 12 ml/min). Since the two HDF techniques showed a
similar effect on small-solute removal, the choice should relie upon t
heir possible advantages or risks.