Intraoperative small bowel endoscopy was performed on 33 occasions in
31 patients with Crohn's disease. The extent of mucosal inflammation w
as compared with that of changes in the external bowel wall: serositis
, fat-wrapping and mural thickening. The influence of endoscopic findi
ngs on surgical management was evaluated. Mucosal inflammation was gen
erally more extensive than serositis (P < 0.01), but less so than mura
l thickening (P < 0.001). The extent of fat-wrapping did not differ fr
om that of mucositis. Of 23 patients undergoing reoperation or with fi
stula or abscess, however, eight had serositis and/or fat-wrapping in
bowel segments without mucosal inflammation. Endoscopic findings influ
enced surgical decisions on 20 of the 33 occasions, limiting planned r
esection in 14, identifying strictures for repair in one, and deciding
against resection in two cases and for extended resection in three. T
hese results suggest that external inflammatory changes are unreliable
guides to the extent of intestinal mucositis and requirements for res
ection in Crohn's disease. By visualizing the mucosa, intraoperative e
nteroscopy can provide information for more precise surgery, thereby l
imiting resection.