G. Petrat et al., ON-DEMAND ANALGESIA WITH PIRITRAMIDE IN CHILDREN - A STUDY ON DOSAGE SPECIFICATION AND SAFETY, European journal of pediatric surgery, 7(1), 1997, pp. 38-41
The results of this study show that postoperative patient-controlled p
ain therapy in children with piritramide is - in a similar way as with
adults - a safe method involving a low incidence of side effects. A s
pecial pump parameter setting is required with larger bolus dose sizes
and longer lockout intervals, not very different from the experience
gained with adults, and which is based on other values than those reco
mmended up to now with morphine for paediatric PCA. Side effects were
rarely observed. The fear of respiratory depression constitutes no rat
ional reason to deny the younger patients this form of analgesia provi
ded that monitoring is guaranteed.