Pneumatosis cystoides intestinalis (PCI), a condition involving submuc
osal or subserosal gas-containing cysts of the wall of the gastrointes
tinal tract, is a rare entity. It is mostly diagnosed between the thir
d and fifth decades of life without a clear sexual predominance. Diffe
rent aetiopathogenetic factors are under discussion, the most probable
being a bacteriologic cause (Clostridium perfringens) in combination
with minimal leaks in the mucosal barrier. There are no pathognomonic
symptoms; the clinical picture ranges from incidental findings to haem
atochezia. Diagnosis is based on plain abdominal film and X-ray follow
ing barium enema. Methods of treatment in symptomatic cases are oxygen
and antibiotic (metronidazole) therapies and, in severe cases, resect
ion of the diseased part of the intestine.