HEPATITIS-C VIRUS-INFECTION AND LIVER-DISEASE IN CHILDREN WITH THALASSEMIA

Authors
LOCASCIULLI A MONGUZZI W TORNOTTI G BIANCO P MASERA G
Citation
A. Locasciulli et al., HEPATITIS-C VIRUS-INFECTION AND LIVER-DISEASE IN CHILDREN WITH THALASSEMIA, Bone marrow transplantation, 12, 1993, pp. 18-20
Citations number
8
Categorie Soggetti
Hematology,Oncology,Immunology
Journal title
Bone marrow transplantation → ACNP
ISSN journal
02683369
Volume
12
Year of publication
1993
Supplement
1
Pages
18 - 20
Database
ISI
SICI code
0268-3369(1993)12:<18:HVALIC>2.0.ZU;2-M
Abstract
Antibody to the recently identified HCV and type of liver disease were investigated in 25 children with homozygous beta thalassemia. All pat ients were tested at regular intervals by second generation ORTHO-ELIS A test. 19/25(76%) patients were found repeatedly positive: in 11 case s seroconversion from anti-HCV- to anti-HCV+ status could be also docu mented. Liver disease was more severe in anti-HCV positive children. S eroconversion however did not produce major changes in liver disease o utcome.