CENTRAL VENOUS CATHETER WITH SUBCUTANEOUS INJECTION PORT (PORT-A-CATH) - 8 YEARS CLINICAL FOLLOW-UP WITH CHILDREN

Long-term intermittent venous access was established in 77 children by means of a central venous catheter (CVC) with a subcutaneous injectio n port (Port-A-Cath; PAC). Seventy of these children were included in this follow-up study. Sixty-three were treated for different malignant diseases, five for cystic fibrosis, one for severe hemophilia and one for central nervous system disease with seizures as the main problem. As of April, 1992, PACs had been in place for 3/12 to 8 3/12 years (c umulative 175 5/12 years) with 2,206 entries into the system. The PACs were used for blood sampling and administration of chemotherapy, anti biotics, fluids, total parenteral nutrition (TPN) and blood products. Portal infection was observed in four patients of which two patients h ad their PAC removed. Catheter dislocation was observed in two and cat heter breakage in one. Portal occlusion, extravasation, thrombosis lea ding to removal of the PAC or other technical or psychological complic ations were not observed. The children continued normal activities, an d the easy venous access decreased emotional stress during treatment. Local doctors were trained to use PACs, through which they administere d maintenance chemotherapy. We conclude that long-time use of PACs in children is safe and has many advantages compared to traditional CVCs in use. Strict indications, meticulous implantation techniques and ade quate handling are, however, mandatory.