Although the association of bone marrow fibrosis with plasma cell dysc
rasias has already been described in several reports, the close relati
onship between these entities still remains unclear. In this report we
describe a patient with clinical and pathologic findings which initia
lly suggested a diagnosis of myelofibrosis, subsequently shown to be c
oexistent with multiple myeloma. Possible explanations for this associ
ation are discussed.