S. Hisano et al., RECIPROCAL SYNAPTIC RELATIONS BETWEEN CRF-IMMUNOREACTIVE AND TRH-IMMUNOREACTIVE NEURONS IN THE PARAVENTRICULAR NUCLEUS OF THE RAT HYPOTHALAMUS, Brain research, 620(2), 1993, pp. 343-346
By double immunoelectron microscopy, we studied synaptic relations bet
ween corticotropin-releasing factor (CRF)-immunoreactive (ir) and thyr
otropin-releasing hormone (TRH)-ir neurons in the paraventricular nucl
eus (PVN) of the rat hypothalamus. CRF-ir and TRH-ir neurons made reci
procal synaptic connections in the medial and periventricular parvocel
lular regions. These results may suggest that both the parvocellular n
eurons interplay on their hypophysiotropic functions within the PVN.