THE STREPTOMYCES-COELICOLOR-GLNR GENE ENCODES A PROTEIN SIMILAR TO OTHER BACTERIAL RESPONSE REGULATORS

Authors
WRAY LV FISHER SH
Citation
Lv. Wray et Sh. Fisher, THE STREPTOMYCES-COELICOLOR-GLNR GENE ENCODES A PROTEIN SIMILAR TO OTHER BACTERIAL RESPONSE REGULATORS, Gene, 130(1), 1993, pp. 145-150
Citations number
35
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
130
Issue
1
Year of publication
1993
Pages
145 - 150
Database
ISI
SICI code
0378-1119(1993)130:1<145:TSGEAP>2.0.ZU;2-9
Abstract
The Streptomyces coelicolor glnR gene positively regulates the transcr iption of the glutamine synthetase-encoding glnA gene. The nucleotide sequence of a 1682-bp DNA segment containing glnR was determined. The deduced amino acid sequence of the GlnR protein was found to be simila r to the sequence of several bacterial response regulators that are kn own to function as transcriptional activators. Primer extension analys is of glnR mRNA identified three transcriptional start points (tsp) up stream from the glnR coding sequence.