Space missions expose humans to a radiation environment of a particula
te composition and intensity not encountered within our biosphere. The
natural radiation environment encountered in Earth orbit is a complex
mixture of charged particles of galactic and solar origin and of thos
e trapped by the geomagnetic field. In addition, secondaries are produ
ced by interaction of cosmic ray primaries with the spacecraft shieldi
ng material. Among this large variety of radiation components in space
, it is likely that the heavy ions are the significant species as far
as radiobiological effects are concerned In addition, a synergistic in
teraction of microgravity and radiation on living systems has been rep
orted in some instances. Based on an admissible risk of 3 % mortality
due to cancers induced during a working career, radiation protection g
uidelines have been developed for this radiation environment.