EPIGASTRIC IMPEDANCE RECORDING FOR MEASURING GASTRIC-EMPTYING IN CHILDREN - HOW USEFUL IS IT

Epigastric impedance recording was used to measure gastric half-emptyi ng time (t1/2) of orange squash in 45 healthy infants and children. Th e relationship between age, body size, and composition and the impedan ce increase after gastric filling was investigated, together with the effects on half-emptying time of adding fat, increasing viscosity, and increasing osmolality in the test meal. The mean t1/2 for orange squa sh was 13.5 min. The increase in impedance per unit volume ingested sh owed a significant inverse relationship with age (r = -0.62, p < 0.001 ), and with various anthropometric variables (r ranged from -0.48 to - 0.80, p < 0.01). No relationship was observed between t,12 and age, se x, body size, or composition. Addition of 1.25% triglyceride or a 600- fold increase in viscosity of the test meal were both accompanied by a significant lengthening of t1/2 (p = 0.005 and p < 0.001, respectivel y), but t1/2 did not alter with a fourfold increase in test meal osmol ality. The test was well tolerated by all subjects, but its usefulness is limited by susceptibility to movement artefact, and also the neces sity to use simple, liquid test meals.