YEAST MITOCHONDRIAL ATP-DEPENDENT PROTEASE - PURIFICATION AND COMPARISON WITH THE HOMOLOGOUS RAT ENZYME AND THE BACTERIAL ATP-DEPENDENT PROTEASE LA

Authors
KUTEJOVA E DURCOVA G SUROVKOVA E KUZELA S
Citation
E. Kutejova et al., YEAST MITOCHONDRIAL ATP-DEPENDENT PROTEASE - PURIFICATION AND COMPARISON WITH THE HOMOLOGOUS RAT ENZYME AND THE BACTERIAL ATP-DEPENDENT PROTEASE LA, FEBS letters, 329(1-2), 1993, pp. 47-50
Citations number
17
Categorie Soggetti
Biophysics,Biology
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
329
Issue
1-2
Year of publication
1993
Pages
47 - 50
Database
ISI
SICI code
0014-5793(1993)329:1-2<47:YMAP-P>2.0.ZU;2-X
Abstract
Homogenous ATP-dependent protease has been isolated for the first time from mitochondria of the yeast Saccharomyces cerevisiae. The enzyme m olecule consists of six 120 kDa subunits. It is a serine protease with an absolute ATP requirement for its activity. Basic enzymatic charact eristics of the yeast protease are similar to those of the correspondi ng rat mitochondrial enzyme and of the E. coli protease La. The yeast enzyme immunochemically cross-reacts with the bacterial protease La.