MECHANISM OF GEL-ELECTROPHORESIS OF DNA - UNEXPECTED FINDINGS

Authors
ZIMM BH
Citation
Bh. Zimm, MECHANISM OF GEL-ELECTROPHORESIS OF DNA - UNEXPECTED FINDINGS, Current opinion in structural biology, 3(3), 1993, pp. 373-376
Citations number
26
Categorie Soggetti
Biology
Journal title
Current opinion in structural biology → ACNP
ISSN journal
0959440X
Volume
3
Issue
3
Year of publication
1993
Pages
373 - 376
Database
ISI
SICI code
0959-440X(1993)3:3<373:MOGOD->2.0.ZU;2-M
Abstract
This review discusses some unresolved problems in understanding the mo lecular mechanism of the electrophoresis of DNA through gels, problems that have come to light only recently. These include: the wide variet y of dependences of the electrophoretic mobility on DNA length, the ef fect of chirality of supercoiling on the mobility, and the formation o f large aggregates of DNA in free-solution electrophoresis in capillar ies.