KINETIC REGULARITIES CONTROLLING DEPHOSPH ORYLATION OF ACETYLCHOLINESTERASE BY PYRIDINIUM ALDOXIMES COIMMOBILIZED WITH THE ENZYME ON A HYDROPHILIC COPOLYMER

Authors
OSINKIN YA ANDRIANOV AK PLATE NA
Citation
Ya. Osinkin et al., KINETIC REGULARITIES CONTROLLING DEPHOSPH ORYLATION OF ACETYLCHOLINESTERASE BY PYRIDINIUM ALDOXIMES COIMMOBILIZED WITH THE ENZYME ON A HYDROPHILIC COPOLYMER, Vysokomolekularnye soedinenia. Seria A, 35(7), 1993, pp. 20000898-20000901
Citations number
10
Categorie Soggetti
Polymer Sciences
Journal title
Vysokomolekularnye soedinenia. Seria A → ACNP
ISSN journal
05075475
Volume
35
Issue
7
Year of publication
1993
Pages
20000898 - 20000901
Database
ISI
SICI code
0507-5475(1993)35:7<20000898:KRCDOO>2.0.ZU;2-4
Abstract
A kinetic scheme describing dephosphorylation of acetylcholinesterase coimmobilized with pyridinium aldoximes on a hydrophilic copolymer is suggested. Kinetic study of the reaction suggests that enhanced reacti vity of the coimmobilized system, compared to the free compounds, is a ssociated with the formation of intermediary emzyme-reactivator comple xes.